In regard to the T1 vs T2 blast, I do agree that the DPA is minimally different. The primary difference is spending only 1 second not doing a lot of damage, versus 1.67 seconds doing not much more. With so many other choices available to a character (In this example, you've got two toggle debuffs, a heal, AM, LR, Cosmic Burst, Irradiate, Proton Volley, Atomic Blast, and eventually a Destiny power), I'd find my time better spent doing any of those than waiting for a filler attack to finish animating. I don't mind slapping the T1 again (or setting it on auto) if simply attacking again is the most expedient thing to do. The incredibly short recharge means that Neutrino Bolt can be its own attack chain. Carpel tunnel is its own over-riding issue, of course, and you have my sympathy.
Of course, if you're talking about an AV at less than 30% health, then mashing attacks might be all that matters.
It's all a matter context (what are your build goals and what content do you find yourself playing?. I find Corruptor blasts (at least until you're dealing with enemies at low health) to be underwhelming, which is perfectly fine with me because the secondaries are packed with awesome buffs/debuffs/controls for setting them up
